Human MAGOHB Recombinant Protein (RPPB3918)

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주문
SKU:
RPPB3918
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
MAGOHB
Synonyms:
mago-nashi homolog B (Drosophila)
Synonyms:
mago
Synonyms:
magoh
Synonyms:
MGN2
Source:
Escherichia Coli
Uniprot:
Q96A72
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Description

Product Name:Human MAGOHB Recombinant Protein
Product Code:RPPB3918
Size:10µg
Species:Human
Target:MAGOHB
Synonyms:mago-nashi homolog B (Drosophila), mago, magoh, MGN2, MAGOHB, MAGOH2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:MAGOHB protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 1mM DTT, 30% glycerol and 0.15M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAVASDF YLRYYVGHKG KFGHEFLEFE FRPDGKLRYA NNSNYKNDVM IRKEAYVHKS VMEELKRIID DSEITKEDDA LWPPPDRVGR QELEIVIGDE HISFTTSKIG SLIDVNQSKD PEGLRVFYYL VQDLKCLVFS LIGLHFKIKP I

Mago-Nashi Homolog B (MAGOHB) is a member of the mago nashi family. MAGOHB involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway. MAGOHB interacts with RBM8A and is a part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, UPF3B, UPF2 and ALYREF/THOC4.

MAGOHB Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 171 amino acids (1-148 a.a.) and having a molecular mass of 19.7kDa.MAGOHB is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:MAGOHB: Involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway. Belongs to the mago nashi family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 12p13.2

Biological Process: mRNA transport; RNA splicing; mRNA processing

UniProt Code:Q96A72
NCBI GenInfo Identifier:8922331
NCBI Gene ID:55110
NCBI Accession:NP_060518.1
UniProt Related Accession:Q96A72
Molecular Weight:17 kDa
NCBI Full Name:protein mago nashi homolog 2 isoform 1
NCBI Synonym Full Names:mago homolog B, exon junction complex subunit
NCBI Official Symbol:MAGOHB  
NCBI Official Synonym Symbols:MGN2; mago; magoh  
NCBI Protein Information:protein mago nashi homolog 2
UniProt Protein Name:Protein mago nashi homolog 2
Protein Family:Protein mago nashi
UniProt Gene Name:MAGOHB  
UniProt Entry Name:MGN2_HUMAN
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