The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD300 is a glycoprotein family of cell surface molecules that regulate a diverse array of cell processes via their triggering and inhibitory receptor functions. The CD300 family of myeloid immunoglobulin receptors includes activating(CD300b, CD300e) and inhibitory members(CD300a, CD300f), as well as CD300c and CD300d, whose function is uncertain.
Product Name:
Human LMIR2/CD300C Recombinant Protein (RPES5058)
Product Code:
RPES5058
Size:
50µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
CMRF35-Like Molecule 6, CLM-6, CD300 Antigen-Like Family Member C, CMRF35-A1, CMRF-35, Immunoglobulin Superfamily Member 16, IgSF16, CD300c, CD300C, CMRF35, CMRF35A, CMRF35A1, IGSF16
Accession:
NP_006669.1
Sequence:
Met 1-Arg 183
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human CD300C (NP_006669.1) extracellular domain (Met 1-Arg 183) was expressed, with a polyhistidine tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
18.4 kDa
AP Mol Mass:
40-45 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.