Human LGALS2 Recombinant Protein (RPPB0275)
- SKU:
- RPPB0275
- Product type:
- Recombinant Protein
- Size:
- 25ug
- Species:
- Human
- Target:
- LGALS2
- Synonyms:
- HL14
- Gal-2
- Beta-galactoside-binding lectin L-14-II
- Lactose-binding lectin 2
- Source:
- Escherichia Coli
- Uniprot:
- P05162
Description
| Product Name: | Human LGALS2 Recombinant Protein |
| Product Code: | RPPB0275 |
| Size: | 25µg |
| Species: | Human |
| Target: | LGALS2 |
| Synonyms: | HL14, Gal-2, Beta-galactoside-binding lectin L-14-II, Lactose-binding lectin 2, S-Lac lectin 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The Galectin-2 His tag 0.5mg/ml protein solution contains 20mM Tris-HCl pH-8, 0.2M NaCl, 10% glycerol & 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG HELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE |
LGALS2 is a soluble beta-galactoside binding lectin that controls cell-to-cell adhesion and cell-to-extracellular matrix interactions and takes part in tumor progression, pre-mRNA splicing and apoptosis. LGALS2 induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-alpha (LTA) with threat of myocardial infarction.
LGALS2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 152 amino acids (1-132 a.a.) and having a molecular mass of 16.8 kDa. The LGALS2 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | LGALS2: This protein binds beta-galactoside. Its physiological function is not yet known. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 22q13.1 Molecular Function:galactoside binding; carbohydrate binding Disease: Myocardial Infarction, Susceptibility To |
| NCBI Summary: | The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P05162 |
| NCBI GenInfo Identifier: | 585388 |
| NCBI Gene ID: | 3957 |
| NCBI Accession: | P05162.3 |
| UniProt Secondary Accession: | P05162,Q6FGY4, |
| UniProt Related Accession: | P05162 |
| Molecular Weight: | 132 |
| NCBI Full Name: | Galectin-2 |
| NCBI Synonym Full Names: | lectin, galactoside-binding, soluble, 2 |
| NCBI Official Symbol: | LGALS2 |
| NCBI Official Synonym Symbols: | HL14 |
| NCBI Protein Information: | galectin-2; gal-2; galectin 2; S-Lac lectin 2; lactose-binding lectin 2; beta-galactoside-binding lectin L-14-II |
| UniProt Protein Name: | Galectin-2 |
| UniProt Synonym Protein Names: | Beta-galactoside-binding lectin L-14-II; HL14; Lactose-binding lectin 2; S-Lac lectin 2 |
| UniProt Gene Name: | LGALS2 |
| UniProt Entry Name: | LEG2_HUMAN |
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