Human LGALS14 Recombinant Protein (RPPB0293)
- SKU:
- RPPB0293
- Product type:
- Recombinant Protein
- Size:
- 5ug
- Species:
- Human
- Target:
- LGALS14
- Synonyms:
- Placental protein 13-like
- Charcot-Leyden crystal protein 2
- CLC2
- Galectin-14
- Source:
- Escherichia Coli
- Uniprot:
- Q8TCE9
Description
| Product Name: | Human LGALS14 Recombinant Protein |
| Product Code: | RPPB0293 |
| Size: | 5µg |
| Species: | Human |
| Target: | LGALS14 |
| Synonyms: | Placental protein 13-like, Charcot-Leyden crystal protein 2, CLC2, Galectin-14, Gal-14, LGALS14, PPL13, MGC22235. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The LGALS14 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSSLPVP YTLPVSLPVG SCVIITGTPI LTFVKDPQLE VNFYTGMDED SDIAFQFRLH FGHPAIMNSR VFGIWRYEEK CYYLPFEDGK PFELCIYVRH KEYKVMVNGQ RIYNFAHRFP PASVKMLQVL RDISLTRVLI SD |
Galectin14, aka LGALS14, is a member of the galectin family of carbohydrate binding proteins. Galectin family members contain one or two carbohydrate recognition domains, which can bind beta-galactoside. The LGALS14 gene is predominantly expressed in the placenta. LGALS14 is expressed intracellularly in the placenta and eosinophils and is released by eosinophils following allergen stimulation. LGALS14 may be involved in the development of allergic inflammation.
LGALS14 Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 162 amino acids (1-139 a.a.) and having a molecular mass of 18.5kDa. The LGALS14 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | LGALS14: 2 isoforms of the human protein are produced by alternative splicing |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: nucleus Molecular Function:carbohydrate binding Biological Process: apoptosis |
| NCBI Summary: | This gene is predominantly expressed in placenta. The encoded protein belongs to the galectin (galaptin/S-lectin) family. The members of galectin family contain one or two carbohydrate recognition domains, which can bind beta-galactoside. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TCE9 |
| NCBI GenInfo Identifier: | 45439325 |
| NCBI Gene ID: | 56891 |
| NCBI Accession: | NP_982297.1 |
| UniProt Secondary Accession: | Q8TCE9,Q7Z4X8, Q96KD4, Q96KD5, Q96KD6, Q9NR03, A8MPV8 B2R530, C5HZ19, |
| UniProt Related Accession: | Q8TCE9 |
| Molecular Weight: | 19,578 Da |
| NCBI Full Name: | placental protein 13-like isoform 2 |
| NCBI Synonym Full Names: | lectin, galactoside-binding, soluble, 14 |
| NCBI Official Symbol: | LGALS14 |
| NCBI Official Synonym Symbols: | CLC2; PPL13 |
| NCBI Protein Information: | placental protein 13-like; gal-14; galectin-14; Charcot-Leyden crystal protein 2; placental protein 13-like protein |
| UniProt Protein Name: | Placental protein 13-like |
| UniProt Synonym Protein Names: | Charcot-Leyden crystal protein 2; CLC2; Galectin-14; Gal-14 |
| UniProt Gene Name: | LGALS14 |
| UniProt Entry Name: | PPL13_HUMAN |
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