Human LFA-3/CD58 Recombinant Protein (RPES1046)
- SKU:
- RPES1046
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Human
Frequently bought together:
Description
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Human LFA-3/CD58 Recombinant Protein
Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes; erythrocytes; endothelial cells; epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells; antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition; the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Product Name: | Human LFA-3/CD58 Recombinant Protein (RPES1046) |
Product Code: | RPES1046 |
Size: | 10µg |
Species: | Human |
Expressed Host: | Human Cells |
Synonyms: | Lymphocyte Function-Associated Antigen 3, Surface Glycoprotein LFA-3, CD58, LFA3?Ag3, CD58 antigen |
Accession: | P19256 |
Sequence: | Phe29-Arg215 |
Fusion tag: | C-Fc |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a Fc tag at the C-terminus. |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Mol Mass: | 48.6 kDa |
AP Mol Mass: | 35-81 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4 . |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |