Human LAYN Recombinant Protein (RPPB3846)
- SKU:
- RPPB3846
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- LAYN
- Synonyms:
- Layilin
- Source:
- Escherichia Coli
- Uniprot:
- Q6UX15
Frequently bought together:
Description
| Product Name: | Human LAYN Recombinant Protein |
| Product Code: | RPPB3846 |
| Size: | 20µg |
| Species: | Human |
| Target: | LAYN |
| Synonyms: | Layilin |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The LAYN solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSATGRLLS ASDLDLRGGQ PVCRGGTQRP CYKVIYFHDT SRRLNFEEAK EACRRDGGQL VSIESEDEQK LIEKFIENLL PSDGDFWIGL RRREEKQSNS TACQDLYAWT DGSISQFRNW YVDEPSCGSE VCVVMYHQPS APAGIGGPYM FQWNDDRCNM KNNFICKYSD EKPAVPSREA EGEETELTTP VLPEETQEED AKKTFKESRE AALNLAY |
LAYN, also known as Layilin, contains 1 c-type lectin domain. This protein is receptor for hyaluronate and Interacts with NF2, RDX and TLN1. The C-terminal domain interacts with the N-terminal domain of RDX.
LAYN Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (22-235) and having a molecular mass of 26.7kDa.LAYN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | LAYN: Receptor for hyaluronate. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, integral Chromosomal Location of Human Ortholog: 11q23.1 Cellular Component: ruffle; cell surface; focal adhesion; integral to membrane Molecular Function:hyaluronic acid binding; carbohydrate binding |
| UniProt Code: | Q6UX15 |
| NCBI GenInfo Identifier: | 74738165 |
| NCBI Gene ID: | 143903 |
| NCBI Accession: | Q6UX15.1 |
| UniProt Secondary Accession: | Q6UX15,Q8TAY8, Q96NC5, Q96NF3, A6NJB0, B4DJU0, |
| UniProt Related Accession: | Q6UX15 |
| Molecular Weight: | 382 |
| NCBI Full Name: | Layilin |
| NCBI Synonym Full Names: | layilin |
| NCBI Official Symbol: | LAYN |
| NCBI Protein Information: | layilin |
| UniProt Protein Name: | Layilin |
| Protein Family: | Layilin |
| UniProt Gene Name: | LAYN |
| UniProt Entry Name: | LAYN_HUMAN |
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