Human KLF3 Recombinant Protein (RPPB3793)

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SKU:
RPPB3793
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
KLF3
Synonyms:
ATP Synthase H+ Transporting
Synonyms:
Mitochondrial Fo Complex Subunit D
Synonyms:
ATP Synthase D Chain Mitochondrial
Synonyms:
ATP Synthase H+ Transporting Mitochondrial F1F0 Subunit D
Source:
Escherichia Coli
Uniprot:
P57682
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Description

Product Name:Human KLF3 Recombinant Protein
Product Code:RPPB3793
Size:20µg
Species:Human
Target:KLF3
Synonyms:ATP Synthase H+ Transporting, Mitochondrial Fo Complex Subunit D, ATP Synthase D Chain Mitochondrial, ATP Synthase H+ Transporting Mitochondrial F1F0 Subunit D, ATPase Subunit D, My032 Protein, ATPQ. Kruppel-Like Factor 3 (Basic), CACCC-Box-Binding Protein BKLF , Basic Kruppel Like Factor, Krueppel-Like Factor 3, Transcript Ch138, BKLF, TEF-2.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The KLF3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMLMFDPV PVKQEAMDPV SVSYPSNYME SMKPNKYGVI YSTPLPEKFF QTPEGLSHGI QMEPVDLTVN KRSSPPSAGN SPSSLKFPSS HRRASPGLSM PSSSPPIKKY SPPSPGVQPF GVPLSMPPVM AAALSRHGIR SPGILPVIQP VVVQPVPFMY TSHLQQPLMV SLSEEMENSS SSMQVPVIES YEKPISQKKI KIEPGIEPQR TDYYPEEMSP PLMNSVSPPQ ALLQENHPSV IVQPGKRPLP VESPDTQRKR RIHRCDYDGC NKVYTKSSHL KAHRRTHTGE KPYKCTWEGC TWKFARSDEL TRHFRKHTGI KPFQCPDCDR SFSRSDHLAL HRKRHMLV

KLF3 belongs to the Sp1-like/KLF family. KLFs is a family of evolutionarily conserved zinc finger-having transcription factors with various regulatory purposes in cell growth, embryogenesis, proliferation and differentiation. KLF3 is Kruppel-like zinc finger which contain transcription factors and take part in hematopoiesis.

KLF3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345) and having a molecular mass of 41.2kDa.KLF3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:KLF3: Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transcription factor; C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 4p14

Cellular Component: nucleus

Molecular Function:DNA binding; metal ion binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development

UniProt Code:P57682
NCBI GenInfo Identifier:12644533
NCBI Gene ID:51274
NCBI Accession:P57682.1
UniProt Secondary Accession:P57682,Q6PIR1, Q86TN0, Q9P2X6,
UniProt Related Accession:P57682
Molecular Weight:25,430 Da
NCBI Full Name:Krueppel-like factor 3
NCBI Synonym Full Names:Kruppel-like factor 3 (basic)
NCBI Official Symbol:KLF3  
NCBI Official Synonym Symbols:BKLF  
NCBI Protein Information:Krueppel-like factor 3; TEF-2; transcript ch138; basic Kruppel-like factor; basic kruppel like factor; basic krueppel-like factor; CACCC-box-binding protein BKLF
UniProt Protein Name:Krueppel-like factor 3
UniProt Synonym Protein Names:Basic krueppel-like factor; CACCC-box-binding protein BKLF; TEF-2
Protein Family:Krueppel-like factor
UniProt Gene Name:KLF3  
UniProt Entry Name:KLF3_HUMAN
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