Human Interleukin6/IL6 Recombinant Protein (RPES1959)

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SKU:
RPES1959
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
Frequently bought together:

Description

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Human Interleukin6/IL6 Recombinant Protein

Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.

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