Human Interleukin3/IL3 Recombinant Protein (RPES1940)

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SKU:
RPES1940
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Interleukin3/IL3 Recombinant Protein

Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

Product Name:Human Interleukin3/IL3 Recombinant Protein (RPES1940)
Product Code:RPES1940
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:ALRH,IL-13,P600,IL13
Accession:P35225
Sequence:Leu25-Asn146
Fusion tag:C-6His
Activity:Measured in a cell proliferation assay using TF?1 human erythroleukemic cells. The ED50 for this effect is 1.5-4.5 ng/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Leu25-Asn146 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:14.3 kDa
AP Mol Mass:13 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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