Human Interleukin-33/IL-33 Recombinant Protein (RPES2397)
- SKU:
- RPES2397
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human Interleukin-33/IL-33 Recombinant Protein
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils; Peyer patches and mesenteric lymph nodes; but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP); activating intracellular molecules in the NF-?B and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
Product Name: | Human Interleukin-33/IL-33 Recombinant Protein (RPES2397) |
Product Code: | RPES2397 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Interleukin-33, IL-33, Interleukin-1 Family Member 11, IL-1F11, Nuclear Factor From High Endothelial Venules, NF-HEV, IL33, C9orf26, IL1F11, NFHEV |
Accession: | O95760 |
Sequence: | Ser112-Thr 270 |
Fusion tag: | N-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Interleukin-33 is produced by our E.coli expression system and the target gene encoding Ser112-Thr270 is expressed with a 6His tag at the N-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 20.3 kDa |
AP Mol Mass: | 21 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Tris;150mM NaCl; 1mM EDTA;pH 8.0. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |