Human Interleukin-33/IL-33 Recombinant Protein (RPES2397)

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SKU:
RPES2397
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
Frequently bought together:

Description

system_update_alt데이터시트

Human Interleukin-33/IL-33 Recombinant Protein

Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils; Peyer patches and mesenteric lymph nodes; but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP); activating intracellular molecules in the NF-?B and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

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