Human Insulin Recombinant Protein (RPES1561)
- SKU:
- RPES1561
- Product type:
- Recombinant Protein
- Host species:
- Yeast
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human Insulin Recombinant Protein
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Product Name: | Human Insulin Recombinant Protein (RPES1561) |
Product Code: | RPES1561 |
Size: | 50µg |
Species: | Human |
Expressed Host: | Yeast |
Synonyms: | IDDM,IDDM1,IDDM2,ILPR,INS,IRDN,MODY10 |
Accession: | P01308 |
Sequence: | Phe1-Lys29&Gly1-Asn21 |
Fusion tag: | |
Activity: | Measured in a serum-free cell proliferation assay using MCF?7 human breast cancer cells.The ED50 for this effect is typically 0.2-1 µg/mL. |
Endotoxin: | Please contact us for more information. |
Protein Construction: | A DNA sequence encoding human insulin B chain (2LGB_B)(Phe1-Lys29) and human insulin A chain (2KXK_A)(Gly1-Asn21) was expressed with a linker AAK. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 6 kDa |
AP Mol Mass: | 6 kDa |
Formulation: | Lyophilized from sterile PBS, pH 7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |