Human Insulin Recombinant Protein (RPES1561)

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SKU:
RPES1561
Product type:
Recombinant Protein
Host species:
Yeast
Reactivity:
Human
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Description

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Human Insulin Recombinant Protein

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Product Name:Human Insulin Recombinant Protein (RPES1561)
Product Code:RPES1561
Size:50µg
Species:Human
Expressed Host:Yeast
Synonyms:IDDM,IDDM1,IDDM2,ILPR,INS,IRDN,MODY10
Accession:P01308
Sequence:Phe1-Lys29&Gly1-Asn21
Fusion tag:
Activity:Measured in a serum-free cell proliferation assay using MCF?7 human breast cancer cells.The ED50 for this effect is typically 0.2-1 µg/mL.
Endotoxin:Please contact us for more information.
Protein Construction:A DNA sequence encoding human insulin B chain (2LGB_B)(Phe1-Lys29) and human insulin A chain (2KXK_A)(Gly1-Asn21) was expressed with a linker AAK.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:6 kDa
AP Mol Mass:6 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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