Human IMP3 Recombinant Protein (RPPB3747)

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SKU:
RPPB3747
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
IMP3
Synonyms:
BRMS2
Synonyms:
C15orf12
Synonyms:
MRPS4
Synonyms:
U3 snoRNP protein IMP3
Source:
Escherichia Coli
Uniprot:
Q9NV31
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Description

Product Name:Human IMP3 Recombinant Protein
Product Code:RPPB3747
Size:20µg
Species:Human
Target:IMP3
Synonyms:BRMS2, C15orf12, MRPS4, U3 snoRNP protein IMP3.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:IMP3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMVRKLKF HEQKLLKQVD FLNWEVTDHN LHELRVLRRY RLQRREDYTR YNQLSRAVRE LARRLRDLPE RDQFRVRASA ALLDKLYALG LVPTRGSLEL CDFVTASSFC RRRLPTVLLK LRMAQHLQAA VAFVEQGHVR VGPDVVTDPA FLVTRSMEDF VTWVDSSKIK RHVLEYNEER DDFDLEA

IMP3 is the human homolog of the yeast Imp3 protein and Essential for the early cleavages during pre-18S ribosomal RNA processing. IMP3 is a Part of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). IMP3 is a member of to the ribosomal protein S4P family and localizes to the nucleoli and interacts with the U3 snoRNP complex. IMP3 contains an S4 domain. U3 small nucleolar ribonucleoprotein protein IMP3 is a protein which in humans is encoded by the IMP3 gene.

IMP3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (1-184 a.a) and having a molecular mass of 24kDa. IMP3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:IMP3: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Belongs to the ribosomal protein S4P family.Protein type: Nucleolus; RNA processing; RNA-bindingChromosomal Location of Human Ortholog: 15q24Cellular Component: nucleolus; nucleoplasm; nucleus; small ribosomal subunit; small subunit processomeMolecular Function: protein binding; rRNA binding; snoRNA binding; structural constituent of ribosomeBiological Process: positive regulation of translational fidelity; rRNA processing
UniProt Protein Details:
NCBI Summary:This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NV31
NCBI GenInfo Identifier:52783099
NCBI Gene ID:55272
NCBI Accession:Q9NV31.1
UniProt Secondary Accession:Q9NV31,Q53G10, B3KQ67
UniProt Related Accession:Q9NV31
Molecular Weight:21,850 Da
NCBI Full Name:U3 small nucleolar ribonucleoprotein protein IMP3
NCBI Synonym Full Names:IMP3, U3 small nucleolar ribonucleoprotein
NCBI Official Symbol:IMP3  
NCBI Official Synonym Symbols:BRMS2; MRPS4; C15orf12  
NCBI Protein Information:U3 small nucleolar ribonucleoprotein protein IMP3
UniProt Protein Name:U3 small nucleolar ribonucleoprotein protein IMP3
UniProt Synonym Protein Names:BRMS2
Protein Family:U3 small nucleolar ribonucleoprotein protein
UniProt Gene Name:IMP3  
UniProt Entry Name:IMP3_HUMAN
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