Human IL6 Recombinant Protein (RPPB0526)
- SKU:
- RPPB0526
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- IL6
- Synonyms:
- BSF2
- HGF
- HSF
- IFNB2
- Source:
- Sf9 Insect cells
- Uniprot:
- P05231
Frequently bought together:
Description
| Product Name: | Human IL6 Recombinant Protein |
| Product Code: | RPPB0526 |
| Size: | 10µg |
| Species: | Human |
| Target: | IL6 |
| Synonyms: | BSF2, HGF, HSF, IFNB2, IL-6. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | IL6 protein (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENNLNLPKMAEKD GCFQSGFNEE TCLVKIITGL LEFEVYLEYL QNRFESSEEQ ARAVQMSTKVLIQFLQKKAK NLDAITTPDP TTNASLLTKL QAQNQWLQDM TTHLILRSFK EFLQSSLRAL RQMHHHHHH |
| Biological Activity: | The ED50, determined by cell proliferation assay using TF-1 human erythroleukemic cell, is 0.2 - 0.8 ng/ml . |
Interleukin-6 or Il-6 is a cytokine with a large assortment of biological functions. IL-6 it has a crucial part in the last differentiation of b-cells into ig-secreting cells. This cytokine also induces myeloma and plasmacytoma growth. Interleukin-6 induces nerve cells differentiation, among hepatocytes it induces acute phase reactants.
IL6 Human Recombinant produced in Baculovirus is a single glycosylated polypeptide chain containing 189 amino acids (30-212aa) and having a molecular mass of 21.6kDa.(Migrates at 18-28kDa on SDS-PAGE under reducing conditions).IL6 is fused to a 6 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
| UniProt Code: | P05231 |
| NCBI GenInfo Identifier: | 124347 |
| NCBI Gene ID: | 3569 |
| NCBI Accession: | P05231.1 |
| UniProt Secondary Accession: | P05231,Q9UCU2, Q9UCU3, Q9UCU4, |
| UniProt Related Accession: | P05231 |
| Molecular Weight: | 212 |
| NCBI Full Name: | Interleukin-6 |
| NCBI Synonym Full Names: | interleukin 6 |
| NCBI Official Symbol: | IL6 |
| NCBI Official Synonym Symbols: | HGF; HSF; BSF2; IL-6; IFNB2 |
| NCBI Protein Information: | interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor |
| UniProt Protein Name: | Interleukin-6 |
| UniProt Synonym Protein Names: | B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL6 |
| UniProt Entry Name: | IL6_HUMAN |
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