Human IL1F10 His Recombinant Protein (RPPB0690)

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SKU:
RPPB0690
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
IL1F10 His
Synonyms:
Interleukin-1 family member 10
Synonyms:
IL-1F10
Synonyms:
FIL1 theta
Synonyms:
Interleukin-1 HY2
Source:
Escherichia Coli
Uniprot:
Q8WWZ1
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Description

Product Name:Human IL1F10 His Recombinant Protein
Product Code:RPPB0690
Size:20µg
Species:Human
Target:IL1F10 His
Synonyms:Interleukin-1 family member 10, IL-1F10, FIL1 theta, Interleukin-1 HY2, IL-1HY2, Interleukin-1 theta, IL-1 theta, IL1F10, FIL1T, IL1HY2, FKSG75, MGC119831, MGC119832, MGC119833, FIL1-theta.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The IL1F10 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICTLPNRGL DRTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW

Human interleukin family 1, member 10 (IL1F10) belongs to the interleukin 1 cytokine family. IL1F10 is expressed in the fetal skin, spleen and tonsil, generally in the basal epithelia of skin and in proliferating B-cells of the tonsil. IL1F10 binds soluble IL1 receptor type 1 and may be implicated in the regulation of adapted and innate immune responses.

IL1F10 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 172 amino acids (1-152) and having a molecular mass of 19.1kDa.IL1F10 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:IL1F10: Binds soluble IL-1 receptor type 1. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytokine

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: extracellular space

Molecular Function:interleukin-1 receptor binding; cytokine activity

Biological Process: cytokine and chemokine mediated signaling pathway

NCBI Summary:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
UniProt Code:Q8WWZ1
NCBI GenInfo Identifier:25008589
NCBI Gene ID:84639
NCBI Accession:Q8WWZ1.1
UniProt Secondary Accession:Q8WWZ1,Q53SR9, Q56AT8, Q7RTZ5, Q969H5, Q9BYX1,
UniProt Related Accession:Q8WWZ1
Molecular Weight:16,943 Da
NCBI Full Name:Interleukin-1 family member 10
NCBI Synonym Full Names:interleukin 1 family, member 10 (theta)
NCBI Official Symbol:IL1F10  
NCBI Official Synonym Symbols:IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta  
NCBI Protein Information:interleukin-1 family member 10; FIL1 theta; IL-1 theta; interleukin-38; interleukin-1 HY2; family of interleukin 1-theta; IL-1F10 (canonical form IL-1F10a); interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta
UniProt Protein Name:Interleukin-1 family member 10
UniProt Synonym Protein Names:Family of interleukin 1-theta; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta; Interleukin-38
UniProt Gene Name:IL1F10  
UniProt Entry Name:IL1FA_HUMAN
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