Human IL15RA/IL5RA Recombinant Protein (RPES1094)
- SKU:
- RPES1094
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human IL15RA/IL5RA Recombinant Protein
Interleukin 15 Receptor alpha (IL-15R?) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15R? chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15R? can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15R? complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and ? heterodimers and enables signaling to cells.
| Product Name: | Human IL15RA/IL5RA Recombinant Protein (RPES1094) |
| Product Code: | RPES1094 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | CD215, IL15RA, CD215 antigen, IL-15 receptor subunit alpha, IL-15RA, IL-15R-alpha, interleukin 15 receptor, alpha, interleukin-15 receptor subunit alpha, MGC104179 |
| Accession: | Q13261 |
| Sequence: | Ile31-Thr 205 |
| Fusion tag: | C-Fc |
| Activity: | Measured by its ability to block human IL-15-induced proliferation of CTLL?2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Interleukin-15 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Ile31-Thr205 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 45.5 kDa |
| AP Mol Mass: | 36-50 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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