The Human IL-4 Monoclonal Antibody PE Conjugated (MP4-25D2) (AGEL2055) offered by Assay Genie is a powerful tool for researchers studying human interleukin-4 (IL-4), a key cytokine involved in immune response regulation. This monoclonal antibody, conjugated with phycoerythrin (PE), is specifically designed to target IL-4, enabling precise detection and analysis in various experimental settings.IL-4 is a crucial signaling molecule that coordinates immune responses, including the regulation of inflammation and allergic reactions. By targeting IL-4 with this conjugated monoclonal antibody, researchers can better understand the role of IL-4 in diseases such as asthma, allergic disorders, and inflammatory conditions.
This antibody is optimized for use in flow cytometry applications, allowing for the detailed examination of IL-4 expression and secretion in different cell populations.With its high specificity and sensitivity, the Human IL-4 Monoclonal Antibody PE Conjugated (MP4-25D2) (AGEL2055) is a valuable tool for investigating the complex functions of IL-4 in immunology research. Its reliability and performance make it an essential component for studies aimed at elucidating the mechanisms underlying immune responses and developing targeted therapies for immune-related disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05112
Gene ID:
3565
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.