The Human IL-4 Monoclonal Antibody (APC-conjugated) MP4-25D2 (AGEL2056) is a cutting-edge tool for researchers studying interleukin-4 (IL-4), a key cytokine involved in immune responses and inflammation. This monoclonal antibody, meticulously developed for excellence, specifically targets and binds to human IL-4, allowing for precise detection and analysis in experimental settings.IL-4 is a crucial signaling molecule that plays a pivotal role in regulating the immune system, influencing processes such as antibody production and T-cell differentiation. By utilizing the APC-conjugated IL-4 antibody, researchers can delve deeper into the functions and interactions of IL-4 in various cell types, paving the way for advancements in immunology, allergy research, and studies on inflammatory conditions.
This high-quality antibody offers researchers a reliable and validated tool for investigating the intricate mechanisms of IL-4 signaling. Whether exploring the role of IL-4 in infectious diseases, allergies, or autoimmune disorders, the Human IL-4 Monoclonal Antibody (APC-conjugated) MP4-25D2 (AGEL2056) provides a valuable resource for elucidating the complexities of the immune response and potential therapeutic interventions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05112
Gene ID:
3565
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.