APC Anti-Human IL-21 Antibody [3A3-N2] (AGEL2052)

(No reviews yet) Write a Review
SKU:
AGEL2052
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Human IL-21 Antibody [3A3-N2]

The Human IL-21 Monoclonal Antibody (APC-conjugated, clone 3A3-N2, AGEL2052) is a cutting-edge tool for researchers studying IL-21, a critical cytokine involved in regulating immune responses and inflammation. This high-quality monoclonal antibody, validated for use in flow cytometry and other applications, specifically targets human IL-21 protein, enabling precise detection and analysis in a variety of cell types.IL-21, a member of the interleukin family, plays a crucial role in modulating immune responses, including the differentiation and function of T and B cells. Dysregulation of IL-21 has been linked to various autoimmune disorders, inflammatory conditions, and cancer, making it a key target for therapeutic development and research investigations.

By using this APC-conjugated monoclonal antibody, researchers can gain valuable insights into the role of IL-21 in immune modulation and disease pathogenesis.With its specificity, sensitivity, and reliability, the Human IL-21 Monoclonal Antibody (clone 3A3-N2, AGEL2052) is an essential tool for advancing research in immunology, oncology, and other fields where understanding IL-21 signaling is crucial. Explore the potential of IL-21 in immune regulation and therapeutic targeting with this state-of-the-art antibody.

Product Title:APC Anti-Human IL-21 Antibody [3A3-N2]
SKU:AGEL2052
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3A3-N2
Synonyms:Interleukin-21;IL-21;Za11;
Host Species:Mouse
Reactivity:Human
Application:ICFCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9HBE4
Gene ID:59067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

0 Reviews

View AllClose

Related Products