Human IGF2BP2 Recombinant Protein (RPES0952)
- SKU:
- RPES0952
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human IGF2BP2 Recombinant Protein
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
Product Name: | Human IGF2BP2 Recombinant Protein (RPES0952) |
Product Code: | RPES0952 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Insulin-Like Growth Factor 2 mRNA-Binding Protein 2, IGF2 mRNA-Binding Protein 2, IMP-2, Hepatocellular Carcinoma Autoantigen p62, IGF-II mRNA-Binding Protein 2, VICKZ Family Member 2, IGF2BP2, IMP2, VICKZ2 |
Accession: | Q9Y6M1 |
Sequence: | Met 1-Thr 220 |
Fusion tag: | C-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 is produced by our E.coli expression system and the target gene encoding Met1-Thr220 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus. |
Purity: | > 80 % as determined by reducing SDS-PAGE. |
Mol Mass: | 27.2 kDa |
AP Mol Mass: | 43 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |