Human IGF2BP2 Recombinant Protein (RPES0952)

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SKU:
RPES0952
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
Frequently bought together:

Description

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Human IGF2BP2 Recombinant Protein

Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.

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