Human IGF-II/IGF2 Recombinant Protein (RPES1602)
- SKU:
- RPES1602
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human IGF-II/IGF2 Recombinant Protein
Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. Members of this family are structurally homologous to proinsulin, and share higher sequence identity. IGF2 is expressed only from the paternally inherited allele and believed to be secreted by the liver and to circulate in the blood. IGF2 possess growth-promoting activity and can stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF2 is influenced by placental lactogen and may play a role in fetal development.
| Product Name: | Human IGF-II/IGF2 Recombinant Protein (RPES1602) |
| Product Code: | RPES1602 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Insulin-Like Growth Factor II, IGF-II, Somatomedin-A, IGF2, PP1446 |
| Accession: | P01344 |
| Sequence: | Ala25-Glu91 |
| Fusion tag: | |
| Activity: | Measured in a serum-free cell proliferation assay using MCF?7 human breast cancer cells. The ED50 for this effect is 15.7 ng/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Long Insulin-Like Growth Factor II is produced by our E.coli expression system and the target gene encoding Ala25-Glu91 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 8.9 kDa |
| AP Mol Mass: | 15 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 5mM Hac, pH ~3.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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