The Human IgD Monoclonal Antibody (PE Conjugated, IA6-2) is a specialized antibody developed by AssayGenie for research applications involving the IgD protein, a key component of the human immune system. This monoclonal antibody, conjugated to phycoerythrin (PE), offers high specificity and sensitivity for detecting and quantifying IgD in various biological samples.IgD is a critical immunoglobulin involved in the activation and regulation of immune responses, particularly in the recognition of antigens and initiation of immune signaling pathways. The IA6-2 antibody specifically targets IgD, enabling researchers to investigate its expression levels and distribution in different cell types and tissues.
This antibody is validated for use in flow cytometry and immunofluorescence assays, providing valuable insights into the role of IgD in immunity and disease.By utilizing the Human IgD Monoclonal Antibody (PE Conjugated, IA6-2), researchers can further explore the functions of IgD in various immunological processes, including antibody-mediated immunity and immune cell activation. This antibody is a valuable tool for studies in immunology, infectious diseases, and autoimmune disorders, contributing to the advancement of knowledge in immune system regulation and therapeutic development.
Product Title:
PE Anti-Human IgD Antibody [IA6-2]
SKU:
AGEL1851
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
IA6-2
Synonyms:
Immunoglobulin heavy constant delta;IGHD;Ig delta chain C region;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01880
Gene ID:
3495
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It has 3 Ig-like domains and exists in a transmembrane and a soluble form. In general, IgD is not secreted and usually its expression is lost after the Ig isotype switch. After antigen binding, IgD signals through the CD79a/CD79b (Igα/Igβ) heterodimer, resulting in the activation of the B cell.