Human IFN a 2b Recombinant Protein (RPPB0386)
- SKU:
- RPPB0386
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- IFN a 2b
- Synonyms:
- Interferon alpha 2b
- IFNA
- INFA2
- MGC125764
- Source:
- Escherichia Coli
- Uniprot:
- Q86UP4
Frequently bought together:
Description
| Product Name: | Human IFN a 2b Recombinant Protein |
| Product Code: | RPPB0386 |
| Size: | 10µg |
| Species: | Human |
| Target: | IFN a 2b |
| Synonyms: | Interferon alpha 2b, IFNA, INFA2, MGC125764, MGC125765. |
| Source: | Escherichia Coli |
| Physical Appearance: | Colorless, clear and transparent solution. |
| Formulation: | IFN-a 2b is supplied in solution (1.48mg/ml) containing 20mM Acetate Buffer (pH 6.0), 0.8%NaCl and 0.005% Polysorbate 80. |
| Stability: | IFN alpha-2b PEG should be stored refrigerated at 2° to 8°C. Vials should be kept in their packaging to protect from light until the time of use. Shaking and freezing should be avoided. |
| Purity: | Greater than 97.0% as determined by SEC-HPLC. |
| Biological Activity: | The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg. |
| UniProt Code: | Q86UP4 |
IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.
Interferon-a 2b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19269 Dalton. The Pegylated IFN-a 2b is produced by attaching a 20kDa mPEG-aldehyde to the N-terminal IFN alpha-2b. Interferon-a 2b is purified by proprietary chromatographic techniques.
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