Human HSPB7 Recombinant Protein (RPPB5255)
- SKU:
- RPPB5255
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- HSPB7
- Synonyms:
- cvHSP
- DKFZp779D0968
- FLJ32733
- HSPB7
- Source:
- Escherichia Coli
- Uniprot:
- Q9UBY9
Description
| Product Name: | Human HSPB7 Recombinant Protein |
| Product Code: | RPPB5255 |
| Size: | 10µg |
| Species: | Human |
| Target: | HSPB7 |
| Synonyms: | cvHSP, DKFZp779D0968, FLJ32733, HSPB7, CVHSP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | HSPB7 Human solution containing 20mM Tris HCl pH-8, 0.2M NaCl, 2mM DTT & 50% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSHRTSSTFR AERSFHSSSS SSSSSTSSSA SRALPAQDPP MEKALSMFSD DFGSFMRPHS EPLAFPARPG GAGNIKTLGD AYEFAVDVRD FSPEDIIVTT SNNHIEVRAE KLAADGTVMN TFAHKCQLPE DVDPTSVTSA LREDGSLTIR ARRHPHTEHV QQTFRTEIKI |
HSPB7 is part of the Heat shock protein beta family. The HSPB family is one of the more diverse families within the group of HSP families. Several members have chaperone-like activities and/or participate in cytoskeletal stabilization. Several members also show a dynamic, stress-induced translocation to SC35 splicing speckles. HSPB7 constitutively localized to SC35 splicing speckles, determined by its N-terminus. HSPB7 does not support refolding though HSPB1 and HSPB5 chaperone heat unfolded substrates and keet them folding competent.
HSPB7 Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 190 amino acids (1-170 a.a.) and having a molecular mass of 20.7 kDa. HSPB7 protein is fused to a 20 amino acid His-Tag at N-terminus and purified by standard chromatography.
| UniProt Protein Function: | HSPB7: Belongs to the small heat shock protein (HSP20) family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Heat shock protein Chromosomal Location of Human Ortholog: 1p36.13 Cellular Component: Cajal body; mitochondrion; cytoplasm; nucleus; actin cytoskeleton Molecular Function:protein C-terminus binding; protein binding; filamin binding Biological Process: regulation of heart contraction; response to unfolded protein |
| UniProt Code: | Q9UBY9 |
| NCBI GenInfo Identifier: | 7657202 |
| NCBI Gene ID: | 27129 |
| NCBI Accession: | NP_055239.1 |
| UniProt Secondary Accession: | Q9UBY9,Q9NU17, B3KQ37, C9K0Y0, |
| UniProt Related Accession: | Q9UBY9 |
| Molecular Weight: | 7,344 Da |
| NCBI Full Name: | heat shock protein beta-7 |
| NCBI Synonym Full Names: | heat shock 27kDa protein family, member 7 (cardiovascular) |
| NCBI Official Symbol: | HSPB7 |
| NCBI Official Synonym Symbols: | cvHSP |
| NCBI Protein Information: | heat shock protein beta-7; cardiovascular heat shock protein; heat shock 27kD protein family, member 7 (cardiovascular) |
| UniProt Protein Name: | Heat shock protein beta-7 |
| UniProt Synonym Protein Names: | Cardiovascular heat shock protein; cvHsp |
| Protein Family: | Heat shock protein |
| UniProt Gene Name: | HSPB7 |
| UniProt Entry Name: | HSPB7_HUMAN |
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