Human HMGB2 Recombinant Protein (RPES0752)

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SKU:
RPES0752
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human HMGB2 Recombinant Protein

High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Product Name:Human HMGB2 Recombinant Protein (RPES0752)
Product Code:RPES0752
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:High Mobility Group Protein B2, High Mobility Group Protein 2, HMG-2, HMGB2, HMG2
Accession:P26583
Sequence:Gly2-Glu209
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human High Mobility Group Protein B2 is produced by our Mammalian expression system and the target gene encoding Gly2-Glu209 is expressed with a 6His tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:25.1 kDa
AP Mol Mass:28 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.2.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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