The Human HLA-DR Monoclonal Antibody PE/Cy7 Conjugated L243 (AGEL0418) is a cutting-edge tool designed for precise and reliable detection of the HLA-DR protein, a crucial component of the human immune system. This monoclonal antibody, conjugated with PE/Cy7, offers exceptional sensitivity and specificity in flow cytometry applications, enabling researchers to accurately analyze and quantify HLA-DR expression on various cell types.HLA-DR, a major histocompatibility complex (MHC) class II molecule, plays a pivotal role in antigen presentation and immune response regulation. Targeting the HLA-DR antigen is essential for investigating immune cell activation, antigen presentation, and immune-mediated diseases.
The L243 antibody specifically binds to the HLA-DR protein, providing researchers with a powerful tool to explore the role of HLA-DR in immunology, infection, autoimmunity, and transplantation research.With its high affinity and excellent performance in flow cytometry experiments, the Human HLA-DR Monoclonal Antibody PE/Cy7 Conjugated L243 (AGEL0418) is a valuable asset for studies focused on understanding the intricate mechanisms of the human immune system. Whether analyzing immune cell subsets, evaluating immune responses, or investigating disease pathology, this antibody offers unparalleled accuracy and reproducibility, contributing to advancements in biomedical research and therapeutic development.
Product Title:
PerCP Anti-Human HLA-DR Antibody [L243]
SKU:
AGEL0418
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
L243
Synonyms:
HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain;MHC class II antigen DRA;HLA-DRA1/DRB1;DRA/DRB1;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Form:
Liquid
Conjugation:
PerCP
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01903 P01911
Gene ID:
3122,3123
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
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