PE/Cyanine5 Anti-Human HLA-DR Antibody [L243] (AGEL0419)

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SKU:
AGEL0419
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
L243
Conjugation:
PE/Cy5
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human HLA-DR Antibody [L243]

The Human HLA-DR Monoclonal Antibody (PE-Cy5 Conjugated) L243 (AGEL0419) offered by Assay Genie is a cutting-edge tool for researchers delving into the intricate world of human HLA-DR proteins. These monoclonal antibodies are painstakingly engineered to specifically target the HLA-DR molecule, a vital component of the human major histocompatibility complex (MHC). With the powerful PE-Cy5 conjugation, this antibody enables precise detection and analysis of HLA-DR in various cell types, paving the way for in-depth studies in immunology, infectious diseases, and autoimmune disorders.HLA-DR molecules are key players in the immune system, responsible for presenting antigens to T-cells and initiating immune responses. The L243 monoclonal antibody, with its high specificity and sensitivity, allows researchers to unravel the intricate functions of HLA-DR in immune recognition and response.

By facilitating the visualization of HLA-DR expression in cells, this antibody empowers scientists to explore the roles of HLA-DR in diseases such as autoimmune disorders, infectious diseases, and transplant rejection.With its robust validation and reliable performance in flow cytometry and immunofluorescence applications, the Human HLA-DR Monoclonal Antibody (PE-Cy5 Conjugated) L243 (AGEL0419) from Assay Genie is a valuable asset for researchers seeking to deepen their understanding of immune responses and antigen presentation mechanisms in human health and disease.

Product Title:PE/Cyanine5 Anti-Human HLA-DR Antibody [L243]
SKU:AGEL0419
Size:20 Tests, 100 Tests, 200 Tests
Clone No:L243
Synonyms:HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain;MHC class II antigen DRA;HLA-DRA1/DRB1;DRA/DRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Cyanine5 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01903 P01911
Gene ID:3122,3123
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

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