Biotin Anti-Human HLA-DR Antibody [L243] (AGEL0414)

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SKU:
AGEL0414
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
L243
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Human HLA-DR Antibody [L243]

The Human HLA-DR Monoclonal Antibody Biotin Conjugated (L243) (AGEL0414) offered by Assay Genie is a powerful tool for researchers studying human immune responses and cell surface markers. This high-quality monoclonal antibody is specifically designed for detecting and analyzing the HLA-DR protein, a critical component of the human immune system.HLA-DR is a major histocompatibility complex (MHC) class II protein found on antigen-presenting cells. It plays a key role in the activation of T-cells and the initiation of adaptive immune responses. The L243 antibody, conjugated with biotin for enhanced detection capabilities, allows for precise targeting and visualization of HLA-DR in various cell types.

Ideal for applications such as flow cytometry, immunohistochemistry, and Western blotting, this monoclonal antibody enables detailed investigations into the expression and function of HLA-DR in both normal and diseased tissues. Its specificity and sensitivity make it an invaluable asset for studies related to immunology, infectious diseases, autoimmune disorders, and transplant rejection.With the Human HLA-DR Monoclonal Antibody Biotin Conjugated (L243) (AGEL0414) from Assay Genie, researchers can delve deeper into the complex mechanisms of human immune responses and pave the way for advancements in personalized medicine and targeted therapies.

Product Title:Biotin Anti-Human HLA-DR Antibody [L243]
SKU:AGEL0414
Size:25µg, 100µg
Clone No:L243
Synonyms:HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain;MHC class II antigen DRA;HLA-DRA1/DRB1;DRA/DRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Biotin Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P01903 P01911
Gene ID:3122,3123
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

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