The HLA-DR Monoclonal Antibody (APC-conjugated L243) is a vital tool for researchers studying the human immune system and immune response pathways. This antibody, produced by Assay Genie, specifically targets the HLA-DR protein, a key player in antigen presentation to T-cells.By utilizing this monoclonal antibody, researchers can accurately detect and analyze HLA-DR expression in various cell types and tissues, aiding in the understanding of immune responses, autoimmune disorders, infectious diseases, and transplant rejection mechanisms.
The APC conjugation allows for easy flow cytometry applications, enabling high sensitivity and specificity in detecting HLA-DR.The HLA-DR Monoclonal Antibody (APC-conjugated L243) is a reliable tool validated for flow cytometry and immunofluorescence applications, providing precise and reproducible results for researchers in immunology, transplantation, and infectious disease fields. Stay at the forefront of immune system research with this high-quality antibody from Assay Genie.
Product Title:
APC Anti-Human HLA-DR Antibody [L243]
SKU:
AGEL0417
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
L243
Synonyms:
HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain;MHC class II antigen DRA;HLA-DRA1/DRB1;DRA/DRB1;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01903 P01911
Gene ID:
3122,3123
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
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