Human HER3/ErbB3 Recombinant Protein (RPES4339)

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SKU:
RPES4339
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human HER3/ErbB3 Recombinant Protein

Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belongs to the protein kinase superfamily,tyr protein kinase family and EGF receptor subfamily.It contains 1 protein kinase domain and it is expressed in Epithelial tissues and brain. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity.

Product Name:Human HER3/ErbB3 Recombinant Protein (RPES4339)
Product Code:RPES4339
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:c-erbB-3,c-erbB3,EEBB3,ErbB-3,erbB3-S,HER3,LCCS2,MDA-BF-1,p180-ErbB3,p45-sErbB3,p85-sErbB3
Accession:NP_001973.2
Sequence:Ser20-Cys331
Fusion tag:C-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Receptor tyrosine-protein kinase ErbB-3 is produced by our Mammalian expression system and the target gene encoding Ser20-Cys331 is expressed with a Fc tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:61.6 kDa
AP Mol Mass:65 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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system_update_alt데이터시트Human HER3/ErbB3 Recombinant Protein ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of
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