Human HBZ Recombinant Protein (RPPB3665)
- SKU:
- RPPB3665
- Product type:
- Recombinant Protein
- Size:
- 25ug
- Species:
- Human
- Target:
- HBZ
- Synonyms:
- Zeta-globin
- HBAZ
- HBZ2
- Hemoglobin subunit zeta
- Source:
- Escherichia Coli
- Uniprot:
- P02008
Description
| Product Name: | Human HBZ Recombinant Protein |
| Product Code: | RPPB3665 |
| Size: | 25µg |
| Species: | Human |
| Target: | HBZ |
| Synonyms: | Zeta-globin, HBAZ, HBZ2, Hemoglobin subunit zeta, Hemoglobin zeta chain,HBZ. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear colorless solution. |
| Formulation: | The HBZ solution contains 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MSLTKTERTI IVSMWAKIST QADTIGTETL ERLFLSHPQT KTYFPHFDLH PGSAQLRAHG SKVVAAVGDA VKSIDDIGGA LSKLSELHAY ILRVDPVNFK LLSHCLLVTL AARFPADFTA EAHAAWDKFL SVVSSVLTEK YRLEHHHHHH |
Hemoglobin subunit zeta (HBZ) is part of the globin family. Hemoglobin Zeta is alpha-like hemoglobin. The HBZ polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life.
HBZ Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 150 amino acids (1-142 a.a.) and having a molecular mass of 16.7 kDa. The HBZ is fused to an 8 amino acid His Tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | HBZ: The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac. Belongs to the globin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: hemoglobin complex Molecular Function:protein binding; iron ion binding; heme binding; oxygen binding; oxygen transporter activity Biological Process: erythrocyte maturation; oxygen transport; negative regulation of transcription from RNA polymerase II promoter |
| UniProt Code: | P02008 |
| NCBI GenInfo Identifier: | 122335 |
| NCBI Gene ID: | |
| NCBI Accession: | P02008.2 |
| Molecular Weight: | |
| NCBI Full Name: | Hemoglobin subunit zeta |
| UniProt Protein Name: | Hemoglobin subunit zeta |
| UniProt Synonym Protein Names: | HBAZ; Hemoglobin zeta chain; Zeta-globin |
| Protein Family: | Hemoglobin |
| UniProt Gene Name: | HBZ |
| UniProt Entry Name: | HBAZ_HUMAN |
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