Human HBZ Recombinant Protein (RPPB3665)

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SKU:
RPPB3665
Product type:
Recombinant Protein
Size:
25ug
Species:
Human
Target:
HBZ
Synonyms:
Zeta-globin
Synonyms:
HBAZ
Synonyms:
HBZ2
Synonyms:
Hemoglobin subunit zeta
Source:
Escherichia Coli
Uniprot:
P02008
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Description

Product Name:Human HBZ Recombinant Protein
Product Code:RPPB3665
Size:25µg
Species:Human
Target:HBZ
Synonyms:Zeta-globin, HBAZ, HBZ2, Hemoglobin subunit zeta, Hemoglobin zeta chain,HBZ.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear colorless solution.
Formulation:The HBZ solution contains 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MSLTKTERTI IVSMWAKIST QADTIGTETL ERLFLSHPQT KTYFPHFDLH PGSAQLRAHG SKVVAAVGDA VKSIDDIGGA LSKLSELHAY ILRVDPVNFK LLSHCLLVTL AARFPADFTA EAHAAWDKFL SVVSSVLTEK YRLEHHHHHH

Hemoglobin subunit zeta (HBZ) is part of the globin family. Hemoglobin Zeta is alpha-like hemoglobin. The HBZ polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life.

HBZ Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 150 amino acids (1-142 a.a.) and having a molecular mass of 16.7 kDa. The HBZ is fused to an 8 amino acid His Tag at C-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:HBZ: The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac. Belongs to the globin family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: hemoglobin complex

Molecular Function:protein binding; iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: erythrocyte maturation; oxygen transport; negative regulation of transcription from RNA polymerase II promoter

UniProt Code:P02008
NCBI GenInfo Identifier:122335
NCBI Gene ID:
NCBI Accession:P02008.2
Molecular Weight:
NCBI Full Name:Hemoglobin subunit zeta
UniProt Protein Name:Hemoglobin subunit zeta
UniProt Synonym Protein Names:HBAZ; Hemoglobin zeta chain; Zeta-globin
Protein Family:Hemoglobin
UniProt Gene Name:HBZ  
UniProt Entry Name:HBAZ_HUMAN
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