Human Grancalcin/GCA Recombinant Protein (RPES5246)

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SKU:
RPES5246
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
Frequently bought together:

Description

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Human Grancalcin/GCA Recombinant Protein

Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin; calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore; Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions; which suggested a role for grancalcin in granule-membrane fusion and degranulation.

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