Human Grancalcin/GCA Recombinant Protein (RPES5246)
- SKU:
- RPES5246
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human Grancalcin/GCA Recombinant Protein
Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin; calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore; Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions; which suggested a role for grancalcin in granule-membrane fusion and degranulation.
Product Name: | Human Grancalcin/GCA Recombinant Protein (RPES5246) |
Product Code: | RPES5246 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Grancalcin, GCA, GCL |
Accession: | P28676 |
Sequence: | Met 1-Ile217 |
Fusion tag: | N-GST |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Grancalcin is produced by our E.coli expression system and the target gene encoding Met1-Ile217 is expressed with a GST tag at the N-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 50.3 kDa |
AP Mol Mass: | 53 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl; 500mM Nacl; pH 8.5 . |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |