Human GDF11/BMP1 Recombinant Protein (RPES0139)

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SKU:
RPES0139
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human GDF11/BMP1 Recombinant Protein

Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.

Product Name:Human GDF11/BMP1 Recombinant Protein (RPES0139)
Product Code:RPES0139
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Growth/differentiation factor 11,GDF-11,Bone morphogenetic protein 11,BMP-11
Accession:O95390
Sequence:Asn299-Ser407
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:12.6 kDa
AP Mol Mass:14 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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