Human G-CSF/CSF3 Recombinant Protein (RPES2407)
- SKU:
- RPES2407
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human G-CSF/CSF3 Recombinant Protein
Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.
Product Name: | Human G-CSF/CSF3 Recombinant Protein (RPES2407) |
Product Code: | RPES2407 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Granulocyte Colony-Stimulating Factor, G-CSF, Pluripoietin, Filgrastim, Lenograstim, CSF3, C17orf33, GCSF |
Accession: | P09919-2 |
Sequence: | Thr31-Pro204 |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human G-CSF is produced by our E.coli expression system and the target gene encoding Thr31-Pro204 is expressed. |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Mol Mass: | 18.8 kDa |
AP Mol Mass: | 16 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.004% Tween 80, 5% Mannitol, pH 4.0. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |