Human Fumarase/FH Recombinant Protein (RPES4400)

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SKU:
RPES4400
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Fumarase/FH Recombinant Protein

Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.

Product Name:Human Fumarase/FH Recombinant Protein (RPES4400)
Product Code:RPES4400
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Fumarate Hydratase Mitochondrial, Fumarase, FH,FMRD,HLRCC,LRCC,MCL,MCUL1
Accession:P07954
Sequence:Ala45-Lys510
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Fumarase is produced by our E.coli expression system and the target gene encoding Ala45-Lys510 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:50.2 kDa
AP Mol Mass:45 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM Tris, pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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