Human Frizzled-4/FZD4 Recombinant Protein (RPES3054)
- SKU:
- RPES3054
- Product type:
- Recombinant Protein
- Host species:
- HEK293 Cells
- Reactivity:
- Human
Frequently bought together:
Description
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Human Frizzled-4/FZD4 Recombinant Protein
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described; however; its expression is not supported by other experimental evidence.
| Product Name: | Human Frizzled-4/FZD4 Recombinant Protein (RPES3054) |
| Product Code: | RPES3054 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | CD344,EVR1,FEVR,Fz-4,Fz4,FZD4S,FzE4,GPCR,hFz4 |
| Accession: | NP_036325.2 |
| Sequence: | Met 1-Glu180 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human FZD4 (NP_036325.2) (Met1-Glu180) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 43.3 kDa |
| Formulation: | Lyophilized from sterile PBS; pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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