Human FGL1 Recombinant Protein (RPES2757)
- SKU:
- RPES2757
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human FGL1 Recombinant Protein
Hepassocin; also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1); is a liver-specific secreted protein belonging to the fibronogen superfamily; whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.
| Product Name: | Human FGL1 Recombinant Protein (RPES2757) |
| Product Code: | RPES2757 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1 |
| Accession: | Q08830 |
| Sequence: | Leu23-Ile312 |
| Fusion tag: | C-His |
| Activity: | Immobilized Human FGL1-His at 5µg/ml(100 ?l/well) can bind Human LAG-3-Fc(Cat: PKSH033597). The ED50 of Human FGL1-His is 0.059µg/mL. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 35 kDa |
| AP Mol Mass: | 35 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris;300mM NaCl; 10% Glycerol;2mMEDTA;pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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