Human FGL1 Recombinant Protein (RPES2737)
- SKU:
- RPES2737
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Human
Frequently bought together:
Description
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Human FGL1 Recombinant Protein
Hepassocin; also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1); is a liver-specific secreted protein belonging to the fibronogen superfamily; whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .
| Product Name: | Human FGL1 Recombinant Protein (RPES2737) |
| Product Code: | RPES2737 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1 |
| Accession: | Q08830 |
| Sequence: | Leu23-Ile312 |
| Fusion tag: | C-mFc |
| Activity: | Immobilized Human LAG-3(Cat: PKSH033596) at 5µg/ml(100 ?l/well) can bind Human FGL1-Fc. The ED50 of Human FGL1-Fc is 2.1 ug/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312(Trehalose) is expressed with a mFc tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 60.6 kDa |
| AP Mol Mass: | 60-65 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; 5% Thehalose; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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