Human FGF2/FGF12 Recombinant Protein (RPES3844)

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SKU:
RPES3844
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human FGF2/FGF12 Recombinant Protein

Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Product Name:Human FGF2/FGF12 Recombinant Protein (RPES3844)
Product Code:RPES3844
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Fibroblast Growth Factor 12, FGF-12, Fibroblast Growth Factor Homologous Factor 1, FHF-1, Myocyte-Activating Factor, FGF12, FGF12B, FHF1
Accession:P61328-2
Sequence:Met 1-Thr181
Fusion tag:
Activity:Immobilized Human FGF-12 at 2ug/ml(100 ?l/well) can bind Human FGFR3-Fc(Cat: PKSH033678). The ED50 of Human FGF-12 is 1.27 ug/ml .
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:20.5 kDa
AP Mol Mass:19 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.5.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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