Human FGF-8F Recombinant Protein (RPES4110)
- SKU:
- RPES4110
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human FGF-8F Recombinant Protein
Fibroblast growth factor 8 (FGF-8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen--dependent growth of mouse mammary carcinoma cells. Mouse FGF-8b shares 100% aa identity with human FGF-8b. FGF-8 is widely expressed during embryogenesis, and mediates epithelial--mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
Product Name: | Human FGF-8F Recombinant Protein (RPES4110) |
Product Code: | RPES4110 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Fibroblast growth factor 8,Androgen-induced growth factor,Heparin-binding growth factor 8,AIGF,HBGF-8,FGF-8B |
Accession: | P55075-4 |
Sequence: | Gln23-Arg244 |
Fusion tag: | N-6His |
Activity: | Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 20-100 ng/ml. |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Fibroblast growth factor 8f is produced by our E.coli expression system and the target gene encoding Gln23-Arg244 is expressed with a 6His tag at the N-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 27.7 kDa |
AP Mol Mass: | 30 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT,pH 7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |