Human FBPase 1/FBP1 Recombinant Protein (RPES3740)
- SKU:
- RPES3740
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human FBPase 1/FBP1 Recombinant Protein
Fructose-1;6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein; which catalyzes the hydrolysis of fructose 1;6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state; or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
| Product Name: | Human FBPase 1/FBP1 Recombinant Protein (RPES3740) |
| Product Code: | RPES3740 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Fructose-1,6-Bisphosphatase 1, FBPase 1, D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP |
| Accession: | P09467 |
| Sequence: | Ala2-Gln338 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fructose-1;6-Bisphosphatase 1 is produced by our E.coli expression system and the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 85 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 37.9 kDa |
| AP Mol Mass: | 38 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 200mM NaCl; 1mM DTT; 1mM EDTA; 20% Glycerol; pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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