PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.
Product Name:
Human FAM20B/Gxk1 Recombinant Protein (RPES3564)
Product Code:
RPES3564
Size:
20µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
gxk1
Accession:
NP_055679.1
Sequence:
Ser31-Leu409
Fusion tag:
N-Fc
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human FAM20B (NP_055679.1)(Ser31-Leu409) was expressed with the fused Fc region of human IgG1 at the N-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
71.4 kDa
AP Mol Mass:
72.2 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
