Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.
Product Name:
Human FABP5 Recombinant Protein (RPES2388)
Product Code:
RPES2388
Size:
50µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Fatty Acid-Binding Protein Epidermal, Epidermal-Type Fatty Acid-Binding Protein, E-FABP, Fatty Acid-Binding Protein 5, Psoriasis-Associated Fatty Acid-Binding Protein Homolog, PA-FABP, FABP5
Accession:
Q01469
Sequence:
Met 1-Glu 135
Fusion tag:
Endotoxin:
Please contact us for more information.
Protein Construction:
A DNA sequence encoding the human FABP5 (Q01469) (Met 1-Glu 135) was expressed and purified.
Purity:
> 92 % as determined by reducing SDS-PAGE.
Mol Mass:
15.2 kDa
Formulation:
Lyophilized from sterile 50mM Tris; pH 8.0
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
