Human DNAJC27 Recombinant Protein (RPPB5209)

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SKU:
RPPB5209
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
DNAJC27
Synonyms:
DnaJ homolog subfamily C member 27
Synonyms:
DnaJ (Hsp40) Homolog
Synonyms:
Subfamily C
Synonyms:
Member 27
Source:
Escherichia Coli
Uniprot:
Q9NZQ0
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Description

Product Name:Human DNAJC27 Recombinant Protein
Product Code:RPPB5209
Size:10µg
Species:Human
Target:DNAJC27
Synonyms:DnaJ homolog subfamily C member 27, DnaJ (Hsp40) Homolog, Subfamily C, Member 27, DNAJC27, Rab and DnaJ domain-containing protein, RABJS, RBJ, dnaJ homolog subfamily C member 27 isoform 1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The DNAJC27 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 50% glycerol, 2mM DTT and 2mM EDTA.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMEANMPK RKEPGRSLRI KVISMGNAEV GKSCIIKRYC EKRFVSKYLA TIGIDYGVTK VHVRDREIKV NIFDMAGHPF FYEVRNEFYK DTQGVILVYD VGQKDSFDAL DAWLAEMKQE LGPHGNMENI IFVVCANKID CTKHRCVDES EGRLWAESKG FLYFETSAQT GEGINEMFQT FYISIVDLCE NGGKRPTTNS SASFTKEQAD AIRRIRNSKD SWDMLGVKPG ASRDEVNKAY RKLAVLLHPD KCVAPGSEDA FKAVVNARTA LLKNIK

DnaJ (Hsp40) Homolog, Subfamily C, Member 27 (DNAJC27) which contains one J domain is a part of the small GTPase superfamily. DNAJC27 is a GTPase which activates the MEK/ERK pathway and induces cell transformation when overexpressed.

DNAJC27 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 296 amino acids (1-273 a.a.) and having a molecular mass of 33.2kDa. DNAJC27 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:DNAJC27: Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Mitochondrial; G protein, monomeric; Chaperone; G protein, monomeric, Rab; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p23.3

Molecular Function:protein binding

UniProt Code:Q9NZQ0
NCBI GenInfo Identifier:74734733
NCBI Gene ID:51277
NCBI Accession:Q9NZQ0.1
UniProt Secondary Accession:Q9NZQ0,Q5JV88, Q86Y24,
UniProt Related Accession:Q9NZQ0
Molecular Weight:20,264 Da
NCBI Full Name:DnaJ homolog subfamily C member 27
NCBI Synonym Full Names:DnaJ heat shock protein family (Hsp40) member C27
NCBI Official Symbol:DNAJC27  
NCBI Official Synonym Symbols:RBJ; RabJS  
NCBI Protein Information:dnaJ homolog subfamily C member 27
UniProt Protein Name:DnaJ homolog subfamily C member 27
UniProt Synonym Protein Names:Rab and DnaJ domain-containing protein
Protein Family:DnaJ homolog subfamily
UniProt Gene Name:DNAJC27  
UniProt Entry Name:DJC27_HUMAN
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