Human Dipeptidase 1/DPEP1 Recombinant Protein (RPES2375)

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SKU:
RPES2375
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Dipeptidase 1/DPEP1 Recombinant Protein

Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics; such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However; DPEP1 expression decreased with pathological differentiation; lymph-node and distant metastasis.

Product Name:Human Dipeptidase 1/DPEP1 Recombinant Protein (RPES2375)
Product Code:RPES2375
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Dipeptidase 1, Dehydropeptidase-I, Microsomal Dipeptidase, Renal Dipeptidase, hRDP, DPEP1, MDP, RDP, MBD1
Accession:P16444
Sequence:Asp17-Ser385
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Dipeptidase 1 is produced by our Mammalian expression system and the target gene encoding Asp17-Ser385 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:42.1 kDa
AP Mol Mass:41 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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