Human CREB3L1/OASIS Recombinant Protein (RPES2053)
- SKU:
- RPES2053
- Product type:
- Recombinant Protein
- Host species:
- HEK293 Cells
- Reactivity:
- Human
Frequently bought together:
Description
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Human CREB3L1/OASIS Recombinant Protein
CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.
| Product Name: | Human CREB3L1/OASIS Recombinant Protein (RPES2053) |
| Product Code: | RPES2053 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | OASIS,PSEC0238 |
| Accession: | Q96BA8-1 |
| Sequence: | Glu396-Ser519 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human CREB3L1 (Q96BA8-1) (Glu396-Ser519) was expressed with a polyhistidine tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 15.2 kDa |
| AP Mol Mass: | 21-31 kDa |
| Formulation: | Lyophilized from sterile PBS, PH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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