Human CRADD/RAIDD Recombinant Protein (RPES3942)

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SKU:
RPES3942
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human CRADD/RAIDD Recombinant Protein

Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues; with particularly high expression in the adult heart; testis; liver; skeletal muscle; fetal liver; and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2; and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.

Product Name:Human CRADD/RAIDD Recombinant Protein (RPES3942)
Product Code:RPES3942
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Death Domain-Containing Protein CRADD, Caspase and RIP Adapter with Death Domain, RIP-Associated Protein with A Death Domain, CRADD, RAIDD
Accession:P78560
Sequence:Met1-Glu199
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human CRADD is produced by our E.coli expression system and the target gene encoding Met1-Glu199 is expressed.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:23 kDa
AP Mol Mass:21 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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