Contactin-2 (CNTN2) is encoded by the CNTN2 gene,which belongs to the immunoglobulin superfamily and contactin family. It contains 4 fibronectin type-III domains and 6 Ig-like C2-type domains. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. CNTN2 may play a role in the formation of axon connections in the developing nervous system. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
Product Name:
Human Contactin 2/CNTN2 Recombinant Protein (RPES1005)
Recombinant Human Transient axonal glycoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Asn1012 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
108.7 kDa
AP Mol Mass:
110-140 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_alt데이터시트Mouse Contactin 2/CNTN2 Recombinant Protein Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous
system_update_alt데이터시트Human Contactin 5/CNTN5 Recombinant Protein Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed mainly in the nervous syste
system_update_alt데이터시트Human Neuropilin-2/NRP2 Recombinant Protein Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with
