Human CHODL Recombinant Protein (RPPB3179)

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SKU:
RPPB3179
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
CHODL
Synonyms:
Chondrolectin
Synonyms:
Transmembrane Protein MT75
Synonyms:
C21orf68
Synonyms:
Chromosome 21 Open Reading Frame 68
Source:
Escherichia Coli
Uniprot:
Q9H9P2
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Description

Product Name:Human CHODL Recombinant Protein
Product Code:RPPB3179
Size:20µg
Species:Human
Target:CHODL
Synonyms:Chondrolectin, Transmembrane Protein MT75, C21orf68, Chromosome 21 Open Reading Frame 68, PRED12, MT75, CHODL.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The CHODL solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSFCRRVVS GQKVCFADFK HPCYKMAYFH ELSSRVSFQE ARLACESEGG VLLSLENEAE QKLIESMLQN LTKPGTGISD GDFWIGLWRN GDGQTSGACP DLYQWSDGSN SQYRNWYTDE PSCGSEKCVV MYHQPTANPG LGGPYLYQWN DDRCNMKHNY ICKYEPEINP TAPVEKPYLT NQPGDTHQNV VVTEAGIIPN

Chondrolectin (CHODL) is a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. The CHODL protein localizes mainly to the perinuclear region.

CHODL Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 220 amino acids (22-216) and having a molecular mass of 24.6 kDa.CHODL is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance.
NCBI Summary:This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
UniProt Code:Q9H9P2
NCBI GenInfo Identifier:20127636
NCBI Gene ID:140578
NCBI Accession:NP_079220
UniProt Secondary Accession:Q9H9P2,Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3, B2R9C0, B4DJB8
UniProt Related Accession:Q9H9P2
Molecular Weight:28,418 Da
NCBI Full Name:chondrolectin isoform a
NCBI Synonym Full Names:chondrolectin
NCBI Official Symbol:CHODL  
NCBI Official Synonym Symbols:MT75; PRED12; C21orf68  
NCBI Protein Information:chondrolectin
UniProt Protein Name:Chondrolectin
UniProt Synonym Protein Names:Transmembrane protein MT75
Protein Family:Chondrolectin
UniProt Gene Name:CHODL  
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