Human Chitotriosidase/CHIT1 Recombinant Protein (RPES0470)

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SKU:
RPES0470
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Chitotriosidase/CHIT1 Recombinant Protein

Chitotriosidase-1 (CHIT1) is a glycoprotein that belongs to the Glycosyl Hydrolase 18 family and Chitinase class II subfamily. It is secreted by cultured macrophages and serves to degrade chitin, chitotriose and chitobiose. CHIT1 may participate in the defense against nematodes and other pathogens. It is highly expressed in the plasma of patients with Gaucher's disease type I, which can be used as diagnostic aid and to evaluate the success of treatment that brings levels back to normal. The amino acid sequence of human CHIT1 is 99%, 76%, 75% and 55% identical to that of chimpanzee, rat, mouse and fruit fly, respectively.

Product Name:Human Chitotriosidase/CHIT1 Recombinant Protein (RPES0470)
Product Code:RPES0470
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Chitotriosidase-1, Chitinase-1, CHIT1,CHI3,CHIT,CHITD
Accession:Q13231
Sequence:Ala22-Asn466
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Chitotriosidase-1 is produced by our Mammalian expression system and the target gene encoding Ala22-Asn466 is expressed with a 6His tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:50.4 kDa
AP Mol Mass:54 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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