Human CGREF1 Recombinant Protein (RPPB3162)
- SKU:
- RPPB3162
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- CGREF1
- Synonyms:
- Cell Growth Regulator With EF-Hand Domain 1
- Cell GrowthRegulatory Gene 11 Protein
- Hydrophobestin
- CGR11
- Source:
- Escherichia Coli
- Uniprot:
- Q99674
Description
| Product Name: | Human CGREF1 Recombinant Protein |
| Product Code: | RPPB3162 |
| Size: | 10µg |
| Species: | Human |
| Target: | CGREF1 |
| Synonyms: | Cell Growth Regulator With EF-Hand Domain 1, Cell GrowthRegulatory Gene 11 Protein, Hydrophobestin, CGR11, Cell Growth Regulator WithEF Hand Domain Protein 1, Cell Growth Regulator With EF Hand Domain 1, Cellgrowth regulator with EF hand domain protein 1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | CGREF1 protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH7.4). |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSAPKDGVT RPDSEVQHQL LPNPFQPGQE QLGLLQSYLK GLGRTEVQLEHLSREQVLLY LFALHDYDQS GQLDGLELLS MLTAALAPGA ANSPTTNPVI LIVDKVLETQ DLNGDGLMTPAELINFPGVA LRHVEPGEPL APSPQEPQAV GRQSLLAKSP LRQETQEAPG PREEAKGQVE ARRESLDPVQEPGGQAEADG DVPGPRGEAE GQAEAKGDAP GPRGEAGGQA EAEGDAPGPR GEAGGQAEAR ENGEEAKELPGETLESKNTQ NDFEVHIVQV ENDEI |
Cell Growth Regulator with EF-Hand Domain 1, also known as CGREF1 is asecreted calcium ion binding protein. CGREF1 includes two EF-hand domains & both EF-hands are essentialfor function. CGREF1 is most likely digested extracellularly by an unfamiliarserine protease generating extremely hydrophobic bioactive peptides. CGREF1 mediates cell-celladhesion in a calcium-dependent manner. In addition, CGREF1 is capable toinhibit growth in more than a few cell lines.
CGREF1 Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 305 amino acids (20-301 a.a) and having amolecular mass of 32.3kDa.CGREF1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CGREF1: Mediates cell-cell adhesion in a calcium-dependent manner. Able to inhibit growth in several cell lines. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2p23.3 Biological Process: negative regulation of cell proliferation; response to stress |
| UniProt Code: | Q99674 |
| NCBI GenInfo Identifier: | 215273950 |
| NCBI Gene ID: | 10669 |
| NCBI Accession: | Q99674.2 |
| UniProt Secondary Accession: | Q99674,Q8N4B7, A6NHV7, B4DXY8, B5MCB7, B5MCC9, B5MCP5 E7EU99, |
| UniProt Related Accession: | Q99674 |
| Molecular Weight: | 47,064 Da |
| NCBI Full Name: | Cell growth regulator with EF hand domain protein 1 |
| NCBI Synonym Full Names: | cell growth regulator with EF-hand domain 1 |
| NCBI Official Symbol: | CGREF1 |
| NCBI Official Synonym Symbols: | CGR11 |
| NCBI Protein Information: | cell growth regulator with EF hand domain protein 1 |
| UniProt Protein Name: | Cell growth regulator with EF hand domain protein 1 |
| UniProt Synonym Protein Names: | Cell growth regulatory gene 11 protein; Hydrophobestin |
| Protein Family: | Cell growth regulator with EF hand domain protein |
| UniProt Gene Name: | CGREF1 |
| UniProt Entry Name: | CGRE1_HUMAN |
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